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KMID : 1149120180150010006
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Journal of the Korean Society for Psoriasis
2018 Volume.15 No. 1 p.6 ~ p.9
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Psoriasis Skin Models in Psoriasis Research
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Jeong In-Jae
Kim Dong-Hyun
Lee Hee-Jung
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Abstract
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Psoriasis is a common immune-mediated chronic inflammatory skin disease. Several cytokines involved in the immunological mechanism of psoriasis have now been identified. Known cytokines are entangled to form a large signaling pathways are currently being studied to find cytokines that play the most important role in pathogenesis. Psoriasis signaling mechanisms have been known through various studies using cells, mouse models, and psoriasis skin models. The psoriasis skin model is an important tool for psoriasis studies. This review summarizes the psoriasis skin model currently in use.
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KEYWORD
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Psoriasis , Skin equivalent , Skin model
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